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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Extracellular calcium-sensing receptor' and Ligand = 'BDBM50175375'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Homo sapiens (Human))		BDBM50175375
PNG
((S)-2-(3-(1-(benzo[b]thiophen-2-yl)-2-methylpropan...)
Show SMILES CC(C)(Cc1cc2ccccc2s1)NC[C@H](O)COc1ccccc1C#N
Show InChI InChI=1S/C22H24N2O2S/c1-22(2,12-19-11-16-7-4-6-10-21(16)27-19)24-14-18(25)15-26-20-9-5-3-8-17(20)13-23/h3-11,18,24-25H,12,14-15H2,1-2H3/t18-/m0/s1
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Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR

Bioorg Med Chem Lett 15: 5478-82 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.095
BindingDB Entry DOI: 10.7270/Q2WS8STX
More data for this
Ligand-Target Pair