Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Focal adhesion kinase 1 (Homo sapiens (Human)) | BDBM50438033 (CHEMBL2409605) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Paris Descartes Curated by ChEMBL | Assay Description Inhibition of FAK (unknown origin) using ULight-poly GT as substrate after 1.6 hrs by TR-FRET assay | J Med Chem 58: 237-51 (2015) Article DOI: 10.1021/jm500784e BindingDB Entry DOI: 10.7270/Q2B27WZC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Focal adhesion kinase 1 (Homo sapiens (Human)) | BDBM50438033 (CHEMBL2409605) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Paris Descartes Curated by ChEMBL | Assay Description Inhibition of pre-activated recombinant full length FAK (unknown origin) using ULight labeled poly(Glu/Tyr) as substrate after 1.6 hrs by TR-FRET ass... | Bioorg Med Chem Lett 23: 4552-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.038 BindingDB Entry DOI: 10.7270/Q2GM88RC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |