Compile Data Set for Download or QSAR

Found 9 hits Enz. Inhib. hit(s) with Target = 'Free fatty acid receptor 1' and Ligand = 'BDBM50434295'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50434295 (CHEMBL2386353) Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Displacement of 3-(2-Fluoro-4-((2'-methyl-4'-(2-(2-((7-nitrobenzo[c][1,2,5]-oxadiazol-4-yl)amino)ethoxy)ethoxy)-[1,1'-biphenyl]-3-yl)-methoxy)phenyl)...				J Med Chem 59: 4849-58 (2016) Article DOI: 10.1021/acs.jmedchem.6b00202 BindingDB Entry DOI: 10.7270/Q24T6M9W
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50434295 (CHEMBL2386353) Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.90	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at FFA1 receptor (unknown origin) expressed in human 132N1 cells measured for 90 secs by Fura-2 AM dye based calcium mobilization as...				J Med Chem 59: 4849-58 (2016) Article DOI: 10.1021/acs.jmedchem.6b00202 BindingDB Entry DOI: 10.7270/Q24T6M9W
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Rattus norvegicus)	BDBM50434295 (CHEMBL2386353) Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	324	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at C-terminal yellow fluorescent protein-fused rat FFA1 receptor transfected in HEK293 cells after 5 mins by BRET assay				ACS Med Chem Lett 4: 441-445 (2013) Article DOI: 10.1021/ml4000673 BindingDB Entry DOI: 10.7270/Q2F1914M
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50434295 (CHEMBL2386353) Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.20	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA1 receptor transfected in human 1321N1 cells by calcium mobilization assay				ACS Med Chem Lett 4: 441-445 (2013) Article DOI: 10.1021/ml4000673 BindingDB Entry DOI: 10.7270/Q2F1914M
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50434295 (CHEMBL2386353) Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at C-terminal yellow fluorescent protein-fused human FFA1 receptor transfected in HEK293 cells after 5 mins by BRET assay in presenc...				ACS Med Chem Lett 4: 441-445 (2013) Article DOI: 10.1021/ml4000673 BindingDB Entry DOI: 10.7270/Q2F1914M
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50434295 (CHEMBL2386353) Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at C-terminal yellow fluorescent protein-fused human FFA1 receptor transfected in HEK293 cells after 5 mins by BRET assay				ACS Med Chem Lett 4: 441-445 (2013) Article DOI: 10.1021/ml4000673 BindingDB Entry DOI: 10.7270/Q2F1914M
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50434295 (CHEMBL2386353) Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA1 receptor transfected in human 1321N1 cells by calcium mobilization assay				ACS Med Chem Lett 4: 441-445 (2013) Article DOI: 10.1021/ml4000673 BindingDB Entry DOI: 10.7270/Q2F1914M
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50434295 (CHEMBL2386353) Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human C-terminal eYFP-tagged FFA1 receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment incubated for 5 mins...				J Med Chem 59: 4849-58 (2016) Article DOI: 10.1021/acs.jmedchem.6b00202 BindingDB Entry DOI: 10.7270/Q24T6M9W
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Mus musculus)	BDBM50434295 (CHEMBL2386353) Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	148	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at mouse FFA1 receptor transfected in human T-REX-293 cells measured for 74 secs by calcium mobilization assay				ACS Med Chem Lett 4: 441-445 (2013) Article DOI: 10.1021/ml4000673 BindingDB Entry DOI: 10.7270/Q2F1914M
					More data for this Ligand-Target Pair