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Found 1 hit Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [489-587]' and Ligand = 'BDBM50073342'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)		BDBM50073342
PNG
(CHEMBL121375 | N-Cyclopentylmethyl-N-[(S)-2-hydrox...)
Show SMILES CNC(=O)N(CCc1ccccc1)C[C@H](O)CN(CC1CCCC1)S(=O)(=O)c1ccc(OC)cc1
Show InChI InChI=1S/C26H37N3O5S/c1-27-26(31)28(17-16-21-8-4-3-5-9-21)19-23(30)20-29(18-22-10-6-7-11-22)35(32,33)25-14-12-24(34-2)13-15-25/h3-5,8-9,12-15,22-23,30H,6-7,10-11,16-20H2,1-2H3,(H,27,31)/t23-/m0/s1
PDB
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PC cid
PC sid
UniChem

Similars
PubMed
 3.40E+3n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity of the compound against HIV-1 protease was determined

Bioorg Med Chem Lett 8: 3631-6 (1999)


BindingDB Entry DOI: 10.7270/Q2MC8Z5V
More data for this
Ligand-Target Pair