Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Galectin-1 (Homo sapiens (Human)) | BDBM50243888![]() (CHEMBL442951 | methyl beta-D-galactopyranoside | m...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.00E+7 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Antagonist activity against human galectin 1 by fluorescence polarization assay | Bioorg Med Chem Lett 24: 3516-20 (2014) Article DOI: 10.1016/j.bmcl.2014.05.063 BindingDB Entry DOI: 10.7270/Q2PC341V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-1 (Homo sapiens (Human)) | BDBM50243888![]() (CHEMBL442951 | methyl beta-D-galactopyranoside | m...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human galectin-1 assessed as dissociation constant by competitive fluorescence polarization assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00371 BindingDB Entry DOI: 10.7270/Q2RB78D7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-1 (Homo sapiens (Human)) | BDBM50243888![]() (CHEMBL442951 | methyl beta-D-galactopyranoside | m...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Binding affinity at recombinant human Galectin 1 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assay | ACS Med Chem Lett 11: 34-39 (2020) Article DOI: 10.1021/acsmedchemlett.9b00396 BindingDB Entry DOI: 10.7270/Q2HX1GZ9 | |||||||||||
More data for this Ligand-Target Pair |