Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Galectin-3 (Homo sapiens (Human)) | BDBM50243888![]() (CHEMBL442951 | methyl beta-D-galactopyranoside | m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 4.40E+6 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Antagonist activity against human galectin 3 by fluorescence polarization assay | Bioorg Med Chem Lett 24: 3516-20 (2014) Article DOI: 10.1016/j.bmcl.2014.05.063 BindingDB Entry DOI: 10.7270/Q2PC341V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50243888![]() (CHEMBL442951 | methyl beta-D-galactopyranoside | m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 4.40E+6 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Binding affinity to human galectin3 by fluorescence polarization assay | Bioorg Med Chem Lett 18: 3691-4 (2008) Article DOI: 10.1016/j.bmcl.2008.05.066 BindingDB Entry DOI: 10.7270/Q22Z15C8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50243888![]() (CHEMBL442951 | methyl beta-D-galactopyranoside | m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 4.40E+6 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human galactin-3 assessed as dissociation constant by competitive fluorescence polarization assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113664 BindingDB Entry DOI: 10.7270/Q2DB85ND | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50243888![]() (CHEMBL442951 | methyl beta-D-galactopyranoside | m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 4.10E+6 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Binding affinity at recombinant human Galectin 3 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assay | ACS Med Chem Lett 11: 34-39 (2020) Article DOI: 10.1021/acsmedchemlett.9b00396 BindingDB Entry DOI: 10.7270/Q2HX1GZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50243888![]() (CHEMBL442951 | methyl beta-D-galactopyranoside | m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 4.40E+6 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human galectin-3 assessed as dissociation constant by competitive fluorescence polarization assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00371 BindingDB Entry DOI: 10.7270/Q2RB78D7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50243888![]() (CHEMBL442951 | methyl beta-D-galactopyranoside | m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 4.40E+6 | n/a | n/a | n/a | n/a | n/a |
The Hashemite University Curated by ChEMBL | Assay Description Binding affinity to human galectin 3 at 20 degC by competitive fluorescence polarization assay | Bioorg Med Chem 18: 5367-78 (2010) Article DOI: 10.1016/j.bmc.2010.05.040 BindingDB Entry DOI: 10.7270/Q2FQ9XMJ | |||||||||||
More data for this Ligand-Target Pair |