Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein [1027-1206,R1052K] (Hepatitis C virus) | BDBM92408 (NS3 protease inhibitor, analog 1) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.89 | n/a | n/a | n/a | n/a | 0.00220 | 1.10E+6 | 8.0 | n/a |
Boehringer Ingelheim (Canada) Ltd. | Assay Description Kinetic analysis of NS3 inhibitor binding experiment were performed using the KinTek stopped flow instrument (SF-2005; excitation, 325 nm; and emissi... | J Biol Chem 286: 11434-43 (2011) Article DOI: 10.1074/jbc.M110.211417 BindingDB Entry DOI: 10.7270/Q2WM1C0T | |||||||||||
More data for this Ligand-Target Pair |