Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [S283T]' and Ligand = 'BDBM347265'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [S283T] (Hepatitis C virus genotype 1b (isolate Japanese) (...)	BDBM347265 (US10202411, Compound 327) Show SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](CF)[C@H]1O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10202411 (2019) BindingDB Entry DOI: 10.7270/Q2RX9F67
					More data for this Ligand-Target Pair