Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine)) | BDBM50126335 (6-[(R)-Amino-(4-chloro-phenyl)-(3-methyl-3H-imidaz...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | MMDB Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of Bovine geranylgeranyltransferase (GGT) | Bioorg Med Chem Lett 14: 5367-70 (2004) Article DOI: 10.1016/j.bmcl.2004.08.012 BindingDB Entry DOI: 10.7270/Q2NS0TC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine)) | BDBM50126335 (6-[(R)-Amino-(4-chloro-phenyl)-(3-methyl-3H-imidaz...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | MMDB Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of bovine Geranylgeranyltransferase | Bioorg Med Chem Lett 14: 5371-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.011 BindingDB Entry DOI: 10.7270/Q2J102N8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50126335 (6-[(R)-Amino-(4-chloro-phenyl)-(3-methyl-3H-imidaz...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&JPRD) Curated by ChEMBL | Assay Description Inhibition of Geranylgeranylprotein transferase-I catalyzed incorporation of [3H]-GGPP into biotinYRASNRSCAIL peptide | Bioorg Med Chem Lett 13: 4365-9 (2003) BindingDB Entry DOI: 10.7270/Q21R6PX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50126335 (6-[(R)-Amino-(4-chloro-phenyl)-(3-methyl-3H-imidaz...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Geranylgeranylprotein transferase-I -catalyzed incorporation of [3H]-GGPP into biotin YRASNRSCAIL substrate | Bioorg Med Chem Lett 13: 1543-7 (2003) BindingDB Entry DOI: 10.7270/Q2M61JNS | |||||||||||
More data for this Ligand-Target Pair |