Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta' and Ligand = 'BDBM50126038'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type-1 subunit beta (Homo sapiens (Human))	BDBM50126038 (5-[1-Hydroxy-1-(3-methyl-3H-imidazol-4-yl)-3-pheny...) Show SMILES Cc1ccccc1-c1cc(ccc1C#N)C(O)(CCc1ccccc1)c1cncn1C Show InChI InChI=1S/C27H25N3O/c1-20-8-6-7-11-24(20)25-16-23(13-12-22(25)17-28)27(31,26-18-29-19-30(26)2)15-14-21-9-4-3-5-10-21/h3-13,16,18-19,31H,14-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human GGTase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide of C-terminal of human K-Ras				Bioorg Med Chem Lett 13: 1293-6 (2003) BindingDB Entry DOI: 10.7270/Q2DV1J8J
					More data for this Ligand-Target Pair