Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucagon-like peptide 1 receptor' and Ligand = 'BDBM189947'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon-like peptide 1 receptor (Homo sapiens (Human))	BDBM189947 (US9175003, 55) Show SMILES Cc1nc(NC(=O)C2CCC2)sc1S(=O)(=O)N1Cc2cc3OC(COc3cc2C[C@H]1C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C(O)=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1 |r| Show InChI InChI=1S/C50H43Cl2N5O9S2/c1-28-49(67-50(54-28)56-46(58)35-3-2-4-35)68(62,63)57-25-37-23-44-43(65-27-45(66-44)34-14-16-38(17-15-34)64-26-31-9-18-39(51)40(52)19-31)22-36(37)21-42(57)47(59)55-41(48(60)61)20-29-5-10-32(11-6-29)33-12-7-30(24-53)8-13-33/h5-19,22-23,35,41-42,45H,2-4,20-21,25-27H2,1H3,(H,55,59)(H,60,61)(H,54,56,58)/t41-,42-,45?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
vTv Therapeutics LLC US Patent					Assay Description The efficacy of GLP-1 receptor agonists was studied in a cAMP functional assay using HEK-293 Cells expressing the cloned human GLP-1 receptor. GLP-1-...				US Patent US9175003 (2015) BindingDB Entry DOI: 10.7270/Q27943FG
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