BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM50325986'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Mus musculus)	BDBM50325986 (3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					Assay Description Binding affinity to GSK-3 beta in mouse D3 cells				Nat Chem Biol 1: 74-84 (2006) Article DOI: 10.1038/nchembio0705-74 BindingDB Entry DOI: 10.7270/Q2MC9118
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50325986 (3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of Protein kinase C eta expressed in Sf-9 cells				Eur J Med Chem 164: 448-470 (2019) Article DOI: 10.1016/j.ejmech.2018.12.073 BindingDB Entry DOI: 10.7270/Q2WH2SVB
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50325986 (3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
The Rockefeller University Curated by ChEMBL					Assay Description Inhibition of GSK3-beta				Trends Pharmacol Sci 25: 471-80 (2004) Article DOI: 10.1016/j.tips.2004.07.006 BindingDB Entry DOI: 10.7270/Q2VX0HG5
The Rockefeller University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50325986 (3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GSK3beta (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112949 BindingDB Entry DOI: 10.7270/Q22V2KVV
TBA					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Mus musculus)	BDBM50325986 (3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					Assay Description Inhibition of GSK-3 beta in mouse D3 cells assessed as induction of neuron specific marker neurofilament-M by immunofluorescence method				Nat Chem Biol 1: 74-84 (2006) Article DOI: 10.1038/nchembio0705-74 BindingDB Entry DOI: 10.7270/Q2MC9118
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Mus musculus)	BDBM50325986 (3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					Assay Description Inhibition of GSK-3 beta in mouse D3 cells assessed as induction of neuron specific marker beta3-tubulin by immunofluorescence method				Nat Chem Biol 1: 74-84 (2006) Article DOI: 10.1038/nchembio0705-74 BindingDB Entry DOI: 10.7270/Q2MC9118
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Mus musculus)	BDBM50325986 (3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					Assay Description Inhibition of GSK-3 beta in mouse D3 cells				Nat Chem Biol 1: 74-84 (2006) Article DOI: 10.1038/nchembio0705-74 BindingDB Entry DOI: 10.7270/Q2MC9118
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Mus musculus)	BDBM50325986 (3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					Assay Description Inhibition of GSK-3 beta in mouse D3 cells assessed as induction of neuron specific marker neurofilament-M by immunofluorescence method				Nat Chem Biol 1: 74-84 (2006) Article DOI: 10.1038/nchembio0705-74 BindingDB Entry DOI: 10.7270/Q2MC9118
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					More data for this Ligand-Target Pair