| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen synthase kinase-3 beta |
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| Ligand | BDBM50325986 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_660462 (CHEMBL1250092) |
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| EC50 | 1000±n/a nM |
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| Citation |  Tan, DS Diversity-oriented synthesis: exploring the intersections between chemistry and biology. Nat Chem Biol1:74-84 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycogen synthase kinase-3 beta |
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| Name: | Glycogen synthase kinase-3 beta |
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| Synonyms: | GSK-3 beta | GSK3B_MOUSE | Gsk3b |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46722.37 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_660471 |
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| Residue: | 420 |
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| Sequence: | MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALF
NFTTQELSSNPPLATILIPPHARIQAAASPPANATAASDTNAGDRGQTNNAASASASNST
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| BDBM50325986 |
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| n/a |
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| Name | BDBM50325986 |
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| Synonyms: | 3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yloxy)phenol | CHEMBL405759 | TWS-119 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14N4O2 |
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| Mol. Mass. | 318.3294 |
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| SMILES | Nc1cccc(c1)-c1cc2c(Oc3cccc(O)c3)ncnc2[nH]1 |
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| Structure | 
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