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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Growth hormone secretagogue receptor type 1' and Ligand = 'BDBM21950'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM21950
PNG
(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Show SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCOC(=O)NCCc1cccc(O)c1 |r|
Show InChI InChI=1S/C25H33N7O5/c1-25(2,26)23(34)28-21(17-36-16-19-7-4-3-5-8-19)22-29-30-31-32(22)13-14-37-24(35)27-12-11-18-9-6-10-20(33)15-18/h3-10,15,21,33H,11-14,16-17,26H2,1-2H3,(H,27,35)(H,28,34)/t21-/m1/s1
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Article
PubMed
n/an/an/an/a 7.90n/an/a7.222



Bristol-Myers Squibb Pharmaceutical Research Institute



Assay Description
The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...

J Med Chem 50: 5890-3 (2007)


Article DOI: 10.1021/jm7010595
BindingDB Entry DOI: 10.7270/Q24J0CCV
More data for this
Ligand-Target Pair