Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM50528539 (CHEMBL4553037) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University Curated by ChEMBL | Assay Description Inhibition of His-tagged human TrkA expressed in baculovirus expression system using Tyr1 peptide as substrate after 1.5 hrs by FRET-based Z-LYTE ass... | J Med Chem 62: 7431-7444 (2019) Article DOI: 10.1021/acs.jmedchem.9b00365 BindingDB Entry DOI: 10.7270/Q2DZ0CSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM50528539 (CHEMBL4553037) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Binding affinity to wild type human partial length TRKA (475 to 790 residues) expressed in mammalian expression system preincubated for 1 hr measured... | J Med Chem 59: 5911-6 (2016) Article DOI: 10.1021/acs.jmedchem.6b00140 BindingDB Entry DOI: 10.7270/Q20G3PMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM50528539 (CHEMBL4553037) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Binding affinity to wild type human partial length TRKA (475 to 790 residues) expressed in mammalian expression system preincubated for 1 hr measured... | J Med Chem 59: 5911-6 (2016) Article DOI: 10.1021/acs.jmedchem.6b00140 BindingDB Entry DOI: 10.7270/Q20G3PMX | |||||||||||
More data for this Ligand-Target Pair |