BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Integrase' and Ligand = 'BDBM50087419'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8076 Curated by ChEMBL					Assay Description In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.				Bioorg Med Chem Lett 14: 2473-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.005 BindingDB Entry DOI: 10.7270/Q2RX9BH1
CNRS UMR 8076 Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
Université Paris-Sud Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Silesia Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase				Bioorg Med Chem 19: 5000-5 (2011) Article DOI: 10.1016/j.bmc.2011.06.054 BindingDB Entry DOI: 10.7270/Q2SN0CTM
University of Silesia Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Silesia Curated by ChEMBL					Assay Description Inhibition of HIV1 recombinant integrase 3'-processing and strand transfer activity using 21-mer U5B/U5A duplex oligonucleotides after 1 hr				Bioorg Med Chem 19: 5000-5 (2011) Article DOI: 10.1016/j.bmc.2011.06.054 BindingDB Entry DOI: 10.7270/Q2SN0CTM
University of Silesia Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	708	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase 3' processing activity				Eur J Med Chem 43: 81-92 (2008) Article DOI: 10.1016/j.ejmech.2007.02.021 BindingDB Entry DOI: 10.7270/Q24170XZ
Jadavpur University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
Université Paris-Sud Curated by ChEMBL					More data for this Ligand-Target Pair