Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM395292'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM395292 (N-[2-(2-Hydroxyethyl)-6-(hydroxymethyl)-2H-indazol...) Show SMILES OCCn1cc2cc(NC(=O)c3cccc(n3)C(F)(F)F)c(CO)cc2n1 Show InChI InChI=1S/C17H15F3N4O3/c18-17(19,20)15-3-1-2-12(21-15)16(27)22-13-6-10-8-24(4-5-25)23-14(10)7-11(13)9-26/h1-3,6-8,25-26H,4-5,9H2,(H,22,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	867	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM DMSO solution of the test substance. 50...				US Patent US10793545 (2020) BindingDB Entry DOI: 10.7270/Q29S1V3D
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM395292 (N-[2-(2-Hydroxyethyl)-6-(hydroxymethyl)-2H-indazol...) Show SMILES OCCn1cc2cc(NC(=O)c3cccc(n3)C(F)(F)F)c(CO)cc2n1 Show InChI InChI=1S/C17H15F3N4O3/c18-17(19,20)15-3-1-2-12(21-15)16(27)22-13-6-10-8-24(4-5-25)23-14(10)7-11(13)9-26/h1-3,6-8,25-26H,4-5,9H2,(H,22,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	867	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM DMSO solution of the test substance. 50...				Bioorg Med Chem Lett 19: 3550-4 (2009) BindingDB Entry DOI: 10.7270/Q2J67K7G
					More data for this Ligand-Target Pair