Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM50076744 (CHEMBL3416733) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Scientific Research"Demokritos" Curated by ChEMBL | Assay Description Inhibition of human recombinant IRAP expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-leucine-7-amido-4-methyl coumarin as su... | J Med Chem 58: 1524-43 (2015) Article DOI: 10.1021/jm501867s BindingDB Entry DOI: 10.7270/Q2Z321B0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM50076744 (CHEMBL3416733) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
National and Kapodistrian University of Athens Curated by ChEMBL | Assay Description Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assay | J Med Chem 59: 9107-9123 (2016) Article DOI: 10.1021/acs.jmedchem.6b01031 BindingDB Entry DOI: 10.7270/Q2PK0JJG | |||||||||||
More data for this Ligand-Target Pair |