Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leukotriene A-4 hydrolase' and Ligand = 'BDBM50266315'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Cavia porcellus)	BDBM50266315 ((2R)-3-((4-cyclohexylphenyl)(phenyl)methylthio)-2-...) Show SMILES C[C@H](CS)C(=O)N[C@@H](CSC(c1ccccc1)c1ccc(cc1)C1CCCCC1)C(O)=O |r| Show InChI InChI=1S/C26H33NO3S2/c1-18(16-31)25(28)27-23(26(29)30)17-32-24(21-10-6-3-7-11-21)22-14-12-20(13-15-22)19-8-4-2-5-9-19/h3,6-7,10-15,18-19,23-24,31H,2,4-5,8-9,16-17H2,1H3,(H,27,28)(H,29,30)/t18-,23+,24?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Santen Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 production				Bioorg Med Chem Lett 19: 442-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.042 BindingDB Entry DOI: 10.7270/Q20K28FC
					More data for this Ligand-Target Pair