BindingDB PrimarySearch

Found 11 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM254603'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM254603 (US10214477, Example 5 \| US9469597, 4 \| US9670136, ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oryzon Genomics S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...				US Patent US10214477 (2019) BindingDB Entry DOI: 10.7270/Q2ZS2ZTB
Oryzon Genomics S.A. US Patent					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM254603 (US10214477, Example 5 \| US9469597, 4 \| US9670136, ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oryzon Genomics S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...				US Patent US10214477 (2019) BindingDB Entry DOI: 10.7270/Q2ZS2ZTB
Oryzon Genomics S.A. US Patent					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM254603 (US10214477, Example 5 \| US9469597, 4 \| US9670136, ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	550	-35.7	n/a	n/a	n/a	n/a	n/a	7.4	25
ORYZON GENOMICS S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...				US Patent US9670136 (2017) BindingDB Entry DOI: 10.7270/Q2PN93SB
ORYZON GENOMICS S.A. US Patent					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM254603 (US10214477, Example 5 \| US9469597, 4 \| US9670136, ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LSD1 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.127993 BindingDB Entry DOI: 10.7270/Q2RB78CS
TBA					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM254603 (US10214477, Example 5 \| US9469597, 4 \| US9670136, ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
East China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal His/GST-tagged LSD1 (172 to 852 residues) expressed in baculovirus infected insect cells using biotin-labe...				Eur J Med Chem 141: 101-112 (2017) Article DOI: 10.1016/j.ejmech.2017.09.073 BindingDB Entry DOI: 10.7270/Q2474DCP
East China Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM254603 (US10214477, Example 5 \| US9469597, 4 \| US9670136, ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Oryzon Genomics S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...				US Patent US10214477 (2019) BindingDB Entry DOI: 10.7270/Q2ZS2ZTB
Oryzon Genomics S.A. US Patent					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM254603 (US10214477, Example 5 \| US9469597, 4 \| US9670136, ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LSD1 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127763 BindingDB Entry DOI: 10.7270/Q23X8BBH
TBA					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM254603 (US10214477, Example 5 \| US9469597, 4 \| US9670136, ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Oryzon Genomics S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...				US Patent US10214477 (2019) BindingDB Entry DOI: 10.7270/Q2ZS2ZTB
Oryzon Genomics S.A. US Patent					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM254603 (US10214477, Example 5 \| US9469597, 4 \| US9670136, ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	292	n/a	n/a	n/a	n/a	7.4	25
ORYZON GENOMICS S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...				US Patent US9670136 (2017) BindingDB Entry DOI: 10.7270/Q2PN93SB
ORYZON GENOMICS S.A. US Patent					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM254603 (US10214477, Example 5 \| US9469597, 4 \| US9670136, ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>20	n/a	n/a	n/a	n/a
East China Normal University Curated by ChEMBL					Assay Description Antagonism of Muscarinic M2 receptors as displacement of concentration response curve of carbachol on isolated guinea-pig left atria				Eur J Med Chem 141: 101-112 (2017) Article DOI: 10.1016/j.ejmech.2017.09.073 BindingDB Entry DOI: 10.7270/Q2474DCP
East China Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM254603 (US10214477, Example 5 \| US9469597, 4 \| US9670136, ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.950	n/a	n/a	n/a	n/a
East China Normal University Curated by ChEMBL					Assay Description Inhibition of LSD1 in human MV-4-11 cells assessed as increase in CD86 mRNA expression after 10 days by SYBR Green dye-bsed RT-qPCR analysis				Eur J Med Chem 141: 101-112 (2017) Article DOI: 10.1016/j.ejmech.2017.09.073 BindingDB Entry DOI: 10.7270/Q2474DCP
East China Normal University Curated by ChEMBL					More data for this Ligand-Target Pair