Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM174928'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM174928 (US9096593, P-2028) Show SMILES COc1cnc2[nH]cc(Cc3ccc(NCc4cncc(F)c4)nc3F)c2c1 Show InChI InChI=1S/C20H17F2N5O/c1-28-16-6-17-14(9-25-20(17)26-11-16)5-13-2-3-18(27-19(13)22)24-8-12-4-15(21)10-23-7-12/h2-4,6-7,9-11H,5,8H2,1H3,(H,24,27)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>100	n/a	n/a	n/a	n/a	7.5	n/a
Plexxikon Inc. US Patent					Assay Description In one assay the biochemical activity IC50 values are determined with respect to inhibition of c-Kit kinase activity, where inhibition of phosphoryla...				US Patent US9096593 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DXR
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