Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM392486'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM392486 (N-[2-(5-cyano-3-pyridyl)-1H- pyrrolo[2,3-b]pyridin...) Show SMILES Cc1n[nH]c(C(=O)Nc2cnc3[nH]c(cc3c2)-c2cncc(c2)C#N)c1C Show InChI InChI=1S/C19H15N7O/c1-10-11(2)25-26-17(10)19(27)23-15-4-13-5-16(24-18(13)22-9-15)14-3-12(6-20)7-21-8-14/h3-5,7-9H,1-2H3,(H,22,24)(H,23,27)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...				J Med Chem 52: 1799-802 (2009) BindingDB Entry DOI: 10.7270/Q2HH6NDZ
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