Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM8826 (3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | J Med Chem 48: 6066-83 (2005) Article DOI: 10.1021/jm050458h BindingDB Entry DOI: 10.7270/Q2WD3XSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM8826 (3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of CKIT | Bioorg Med Chem Lett 16: 4326-30 (2006) Article DOI: 10.1016/j.bmcl.2006.05.057 BindingDB Entry DOI: 10.7270/Q2W958S9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM8826 (3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Punjabi University Curated by ChEMBL | Assay Description Inhibition of c-Kit by HTRF method | Eur J Med Chem 45: 393-404 (2010) Article DOI: 10.1016/j.ejmech.2009.09.013 BindingDB Entry DOI: 10.7270/Q2RX9C6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM8826 (3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.03 | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian University Curated by ChEMBL | Assay Description Inhibition of cKIT | J Mol Graph Model 26: 236-45 (2007) Article DOI: 10.1016/j.jmgm.2006.12.001 BindingDB Entry DOI: 10.7270/Q2GQ7019 | |||||||||||
More data for this Ligand-Target Pair |