Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Membrane primary amine oxidase (Rattus norvegicus (Rat)) | BDBM128993 (US8802679, 69) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9.80 | n/a | n/a | n/a | n/a | n/a | 25 |
Astellas Pharma Inc. US Patent | Assay Description A rat VAP-enzyme 1 (SSAO) activity was measured by a radiochemistry-enzymatic assay using 14C-benzylamine as an artificial substrate. An enzyme suspe... | US Patent US8802679 (2014) BindingDB Entry DOI: 10.7270/Q2M61HZD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Membrane primary amine oxidase (Homo sapiens (Human)) | BDBM128993 (US8802679, 69) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba, Ibaraki 305-8585, Japan. Electronic address: susumu.yamaki@astellas.com. Curated by ChEMBL | Assay Description Inhibition of human VAP-1 expressed in CHO cells preincubated for 20 mins followed by [14C]-benzylamine addition measured after 1 hr by scintillation... | Bioorg Med Chem 25: 6024-6038 (2017) Article DOI: 10.1016/j.bmc.2017.09.036 BindingDB Entry DOI: 10.7270/Q2B27XR3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Membrane primary amine oxidase (Homo sapiens (Human)) | BDBM128993 (US8802679, 69) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | 25 |
Astellas Pharma Inc. US Patent | Assay Description A human VAP-1 enzyme (SSAO) activity was measured by a radiochemistry-enzymatic assay using 14C-benzylamine as an artificial substrate. An enzyme sus... | US Patent US8802679 (2014) BindingDB Entry DOI: 10.7270/Q2M61HZD | |||||||||||
More data for this Ligand-Target Pair |