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Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50232459'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50232459
PNG
(CHEMBL4094126)
Show SMILES c1ccc(nc1)C#Cc1ccc(cc1)C#Cc1ccccn1
Show InChI InChI=1S/C20H12N2/c1-3-15-21-19(5-1)13-11-17-7-9-18(10-8-17)12-14-20-6-2-4-16-22-20/h1-10,15-16H
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PC cid
PC sid
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Article
PubMed
n/an/a 1.21E+3n/an/an/an/an/an/a



Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL


Assay Description
Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed...

Eur J Med Chem 127: 567-576 (2017)


Article DOI: 10.1016/j.ejmech.2017.01.013
BindingDB Entry DOI: 10.7270/Q2736T4T
More data for this
Ligand-Target Pair