BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 6' and Ligand = 'BDBM26431'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM26431 ((2R)-2-aminopentanedioic acid \| CHEMBL76232 \| D-Gl...) Show SMILES N[C@H](CCC(O)=O)C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8.22E+4	n/a	n/a	n/a	n/a
Univ. Rouen Curated by ChEMBL					Assay Description Agonist activity at rat mGluR6 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assay				Bioorg Med Chem Lett 25: 2523-6 (2015) Article DOI: 10.1016/j.bmcl.2015.04.043 BindingDB Entry DOI: 10.7270/Q21Z464C
Univ. Rouen Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Homo sapiens (Human))	BDBM26431 ((2R)-2-aminopentanedioic acid \| CHEMBL76232 \| D-Gl...) Show SMILES N[C@H](CCC(O)=O)C(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for the inhibition of Metabotropic glutamate receptor 6				J Med Chem 41: 1641-50 (1998) Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Homo sapiens (Human))	BDBM26431 ((2R)-2-aminopentanedioic acid \| CHEMBL76232 \| D-Gl...) Show SMILES N[C@H](CCC(O)=O)C(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.70E+5	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Agonist activity at recombinant GluR6				Eur J Med Chem 45: 69-77 (2010) Article DOI: 10.1016/j.ejmech.2009.09.025 BindingDB Entry DOI: 10.7270/Q28S4QVF
Universit£t Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM26431 ((2R)-2-aminopentanedioic acid \| CHEMBL76232 \| D-Gl...) Show SMILES N[C@H](CCC(O)=O)C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Effect on Metabotropic glutamate receptor 6				J Med Chem 40: 3700-5 (1997) Article DOI: 10.1021/jm9703597 BindingDB Entry DOI: 10.7270/Q2W66MF9
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Homo sapiens (Human))	BDBM26431 ((2R)-2-aminopentanedioic acid \| CHEMBL76232 \| D-Gl...) Show SMILES N[C@H](CCC(O)=O)C(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonistic activity at mGlu6 receptor expressed in CHO cells				J Med Chem 39: 3188-94 (1996) Article DOI: 10.1021/jm9602569 BindingDB Entry DOI: 10.7270/Q2M909BH
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair