Found 4 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 6' and Ligand = 'BDBM50004051' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 6
(Rattus norvegicus (Rat)) | BDBM50004051
(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)Show InChI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10) | UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Case Western Reserve University
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 305: 131-42 (2003)
Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 6
(Homo sapiens (Human)) | BDBM50004051
(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)Show InChI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University
Curated by PDSP Ki Database
| |
Annu Rev Pharmacol Toxicol 37: 205-37 (1997)
Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 6
(Homo sapiens (Human)) | BDBM50004051
(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)Show InChI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a |
Georgetown University Medical Center
Curated by ChEMBL
| Assay Description Compound was tested for the inhibition of Metabotropic glutamate receptor 6 |
J Med Chem 41: 1641-50 (1998)
Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 6
(Rattus norvegicus (Rat)) | BDBM50004051
(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)Show InChI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10) | UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid PDB UniChem
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| Article
| n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Tested for the agonistic activity against Metabotropic glutamate receptor 6 |
Bioorg Med Chem Lett 7: 601-606 (1997)
Article DOI: 10.1016/S0960-894X(97)00068-1 BindingDB Entry DOI: 10.7270/Q27944QG |
More data for this Ligand-Target Pair | |