Found 3 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 8' and Ligand = 'BDBM50004051' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 8
(Homo sapiens (Human)) | BDBM50004051
(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)Show InChI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University
Curated by PDSP Ki Database
| |
Annu Rev Pharmacol Toxicol 37: 205-37 (1997)
Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Metabotropic glutamate receptor 8
(Rattus norvegicus (Rat)) | BDBM50004051
(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)Show InChI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Case Western Reserve University
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 305: 131-42 (2003)
Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Metabotropic glutamate receptor 8
(Homo sapiens (Human)) | BDBM50004051
(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)Show InChI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Inhibitory concentration against [3H]1 binding to recombinant human Metabotropic glutamate receptor 8 |
Bioorg Med Chem Lett 15: 349-51 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.093 BindingDB Entry DOI: 10.7270/Q2G161M2 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |