Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50347936'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50347936 (CHEMBL1802640) Show SMILES CNC(=O)c1ccc(CO)c(c1)-n1c(C)cc(OCc2ccc(F)cc2F)c(Br)c1=O |(13.61,-21.01,;13.57,-19.47,;14.89,-18.67,;16.24,-19.41,;14.86,-17.13,;16.19,-16.36,;16.18,-14.81,;14.85,-14.05,;14.84,-12.51,;16.17,-11.73,;13.53,-14.83,;13.52,-16.37,;12.19,-14.06,;12.19,-12.51,;13.52,-11.73,;10.85,-11.74,;9.53,-12.51,;8.19,-11.74,;6.86,-12.52,;5.52,-11.75,;4.2,-12.52,;2.87,-11.75,;2.86,-10.21,;1.53,-9.44,;4.2,-9.43,;5.53,-10.2,;6.87,-9.44,;9.52,-14.06,;8.19,-14.83,;10.86,-14.83,;10.86,-16.37,)| Show InChI InChI=1S/C22H19BrF2N2O4/c1-12-7-19(31-11-15-5-6-16(24)9-17(15)25)20(23)22(30)27(12)18-8-13(21(29)26-2)3-4-14(18)10-28/h3-9,28H,10-11H2,1-2H3,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as phosphorylation FITC-labeled Hsp27 after 60 mins by fluorescence based cascade assay				Bioorg Med Chem Lett 21: 4066-71 (2011) Article DOI: 10.1016/j.bmcl.2011.04.121 BindingDB Entry DOI: 10.7270/Q2SB46R2
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