Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM208986'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM208986 (US9233167, a-6-mPEG5-O-Morphine) Show SMILES COCCOCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:29:37:20:35.33.34,25:24:20:35.33.34| Show InChI InChI=1S/C28H43NO9/c1-29-8-7-27-24-20-3-4-21(30)25(24)38-26(27)22(5-6-28(27,31)23(29)19-20)37-18-17-36-16-15-35-14-13-34-12-11-33-10-9-32-2/h3-4,22-23,26,30-31H,5-19H2,1-2H3/t22-,23?,26-,27-,28+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	39.4	-42.3	n/a	n/a	n/a	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM208986 (US9233167, a-6-mPEG5-O-Morphine) Show SMILES COCCOCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:29:37:20:35.33.34,25:24:20:35.33.34| Show InChI InChI=1S/C28H43NO9/c1-29-8-7-27-24-20-3-4-21(30)25(24)38-26(27)22(5-6-28(27,31)23(29)19-20)37-18-17-36-16-15-35-14-13-34-12-11-33-10-9-32-2/h3-4,22-23,26,30-31H,5-19H2,1-2H3/t22-,23?,26-,27-,28+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	157	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, suspensions of cells expressing either the mu, kappa or delta opioid receptors were prepared in buffer containing 0.5 mM isobutyl-methyl xan...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair