BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50012477'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50012477 (1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.0240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes				Bioorg Med Chem 22: 4581-6 (2014) Article DOI: 10.1016/j.bmc.2014.07.033 BindingDB Entry DOI: 10.7270/Q2P270WT
Clinical Research Institute of Montreal Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50012477 (1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	0.0240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1				J Med Chem 43: 381-91 (2000) BindingDB Entry DOI: 10.7270/Q2DN45RB
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50012477 (1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur Curated by ChEMBL					Assay Description Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1				J Med Chem 33: 2456-64 (1990) BindingDB Entry DOI: 10.7270/Q21Z451M
Universit£ Louis Pasteur Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50012477 (1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.0190	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contraction				Bioorg Med Chem 22: 4581-6 (2014) Article DOI: 10.1016/j.bmc.2014.07.033 BindingDB Entry DOI: 10.7270/Q2P270WT
Clinical Research Institute of Montreal Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50012477 (1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.00490	n/a	n/a	n/a	n/a
United States Army CCDC Chemical Biological Center Curated by ChEMBL					Assay Description Agonist activity at human MOR expressed in CHO-K1 cells assessed as cAMP accumulation incubated for 30 mins and measured after 1 hr by Eu-cAMP tracer...				ACS Med Chem Lett 10: 1568-1572 (2019) Article DOI: 10.1021/acsmedchemlett.9b00404 BindingDB Entry DOI: 10.7270/Q2JD5175
					More data for this Ligand-Target Pair