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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50146020'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50146020
PNG
(2-Amino-N-(5-{[2-amino-3-(4-hydroxy-phenyl)-propio...)
Show SMILES Cl.Cl.Cc1nc(CNC(=O)C(N)Cc2ccc(O)cc2)c(=O)[nH]c1CNC(=O)C(N)Cc1ccc(O)cc1
Show InChI InChI=1S/C25H30N6O5/c1-14-21(12-28-23(34)19(26)10-15-2-6-17(32)7-3-15)31-25(36)22(30-14)13-29-24(35)20(27)11-16-4-8-18(33)9-5-16/h2-9,19-20,32-33H,10-13,26-27H2,1H3,(H,28,34)(H,29,35)(H,31,36)
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Article
PubMed
 460n/an/an/an/an/an/an/an/a



National Institutes of Environmental Health Sciences

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards Opioid receptor mu 1 by displacing [3H]DAGO radioligand in rat brain P2 synaptosomes membranes.

J Med Chem 47: 2599-610 (2004)


Article DOI: 10.1021/jm0304616
BindingDB Entry DOI: 10.7270/Q2RB755V
More data for this
Ligand-Target Pair