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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Ligand = 'BDBM50427127'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M2


(RAT)		BDBM50427127
PNG
(CHEMBL2323442)
Show SMILES CN1[C@@H]2C[C@H](OC(C)=O)[C@@H]1C[C@@H](C2)OC(=O)c1ccccc1[N+]([O-])=O |r,TLB:5:4:1:11.12.10,THB:13:11:1:3.4|
Show InChI InChI=1S/C17H20N2O6/c1-10(20)24-16-8-11-7-12(9-15(16)18(11)2)25-17(21)13-5-3-4-6-14(13)19(22)23/h3-6,11-12,15-16H,7-9H2,1-2H3/t11-,12+,15-,16-/m0/s1
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Similars
Article
PubMed
 9.80E+3n/an/an/an/an/an/an/an/a



Shanghai Jiao Tong University School of Medicine

Curated by ChEMBL


Assay Description
Displacement of [3H]NMS from muscarinic M2 receptor in Sprague-Dawley rat left atria after 60 mins

Bioorg Med Chem 21: 1234-9 (2013)


Article DOI: 10.1016/j.bmc.2012.12.052
BindingDB Entry DOI: 10.7270/Q2DF6SHB
More data for this
Ligand-Target Pair