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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Ligand = 'BDBM50518582'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50518582
PNG
(CHEMBL4441786)
Show SMILES O=C(OCc1ccccc1)N(C1CN2CCC1CC2)c1ccccc1 |TLB:10:11:14.15:17.18,(26.99,-23.41,;27.05,-21.87,;28.41,-21.15,;29.72,-21.97,;31.08,-21.25,;32.38,-22.07,;33.74,-21.35,;33.8,-19.81,;32.48,-18.99,;31.13,-19.72,;25.74,-21.05,;24.38,-21.78,;24.03,-23.21,;22.55,-22.7,;22.54,-20.67,;23.14,-19.41,;23.17,-21.32,;21.46,-21.78,;21.06,-23.22,;25.8,-19.51,;27.16,-18.8,;27.22,-17.26,;25.91,-16.44,;24.55,-17.17,;24.5,-18.71,)|
Show InChI InChI=1S/C21H24N2O2/c24-21(25-16-17-7-3-1-4-8-17)23(19-9-5-2-6-10-19)20-15-22-13-11-18(20)12-14-22/h1-10,18,20H,11-16H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 120n/an/an/an/an/an/an/an/a



University of Kentucky

Curated by ChEMBL


Assay Description
Displacement of [3H]NMS from human M2 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry method

Bioorg Med Chem Lett 29: 471-476 (2019)


Article DOI: 10.1016/j.bmcl.2018.12.022
BindingDB Entry DOI: 10.7270/Q2NP27SC
More data for this
Ligand-Target Pair