Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM85438'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Rattus norvegicus (Rat))	BDBM85438 (NEP inhibitor, 6r) Show SMILES CN(C)C(=O)c1ccnc(NC(=O)C(CS)Cc2ccccc2)c1 Show InChI InChI=1S/C18H21N3O2S/c1-21(2)18(23)14-8-9-19-16(11-14)20-17(22)15(12-24)10-13-6-4-3-5-7-13/h3-9,11,15,24H,10,12H2,1-2H3,(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	25
R&D, Zambon Group Spa					Assay Description Enzyme inhibition assay using neutrol endopeptiase EC 3.4.24.11 (NEP).				J Enzym Inhib 12: 155-60 (1997) Article DOI: 10.3109/14756369709035816 BindingDB Entry DOI: 10.7270/Q2FQ9V4F
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