Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuronal acetylcholine receptor subunit alpha-4/beta-4 (Rattus norvegicus (Rat)) | BDBM221048 (US9284322, varenicline | US9303017, Varenicline) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem | PDB US Patent | 28 | -40.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Georgetown University; Duke University US Patent | Assay Description Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm^2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris.... | US Patent US9303017 (2016) BindingDB Entry DOI: 10.7270/Q25X27SF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |