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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Opioid growth factor receptor-like protein 1' and Ligand = 'BDBM220383'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Opioid growth factor receptor-like protein 1


(Homo sapiens (Human))
BDBM220383
PNG
(US9290488, ZA04)
Show SMILES N[C@@H]1CN([C@@H]1C(O)=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3[C@H]2C[C@@H]3C[C@H](C2)CCCC3)c1=O |r,THB:26:25:17.18.24:20.22.21|
Show InChI InChI=1S/C30H41N5O3/c31-24-17-33(27(24)30(37)38)28-29(36)35(26-11-4-3-10-25(26)32-28)23-15-20-8-5-9-21(16-23)34(20)22-13-18-6-1-2-7-19(12-18)14-22/h3-4,10-11,18-24,27H,1-2,5-9,12-17,31H2,(H,37,38)/t18-,19+,20-,21+,22-,23+,24-,27+/m1/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.98 -49.7n/an/an/an/an/a7.425



Purdue Pharma L.P.

US Patent


Assay Description
Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in a ...


US Patent US9290488 (2016)


BindingDB Entry DOI: 10.7270/Q2GF0SCW
More data for this
Ligand-Target Pair
Opioid growth factor receptor-like protein 1


(Homo sapiens (Human))
BDBM220383
PNG
(US9290488, ZA04)
Show SMILES N[C@@H]1CN([C@@H]1C(O)=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3[C@H]2C[C@@H]3C[C@H](C2)CCCC3)c1=O |r,THB:26:25:17.18.24:20.22.21|
Show InChI InChI=1S/C30H41N5O3/c31-24-17-33(27(24)30(37)38)28-29(36)35(26-11-4-3-10-25(26)32-28)23-15-20-8-5-9-21(16-23)34(20)22-13-18-6-1-2-7-19(12-18)14-22/h3-4,10-11,18-24,27H,1-2,5-9,12-17,31H2,(H,37,38)/t18-,19+,20-,21+,22-,23+,24-,27+/m1/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 5.84n/an/a7.425



Purdue Pharma L.P.

US Patent


Assay Description
ORL-1 membrane solution was prepared by sequentially adding final concentrations of 0.066 μg/μL ORL-1 membrane protein, 10 μg/mL saponin, 3 ...


US Patent US9290488 (2016)


BindingDB Entry DOI: 10.7270/Q2GF0SCW
More data for this
Ligand-Target Pair