Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-alpha [197-447]' and Ligand = 'BDBM35103'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM35103 (biarylether amide quinoline, 4c) Show SMILES CC(C)NC(=O)c1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1 Show InChI InChI=1S/C33H27F3N2O2/c1-21(2)38-32(39)24-12-7-14-27(19-24)40-26-13-6-11-23(18-26)30-25(17-22-9-4-3-5-10-22)20-37-31-28(30)15-8-16-29(31)33(34,35)36/h3-16,18-21H,17H2,1-2H3,(H,38,39)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
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