Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM291362'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM291362 (2-(1H-Indol-4-yl)-8-(4-methyl-piperazin-1-ylmethyl...) Show SMILES CN1CCN(Cc2cnc3oc4c(nc(nc4c3c2)-c2cccc3[nH]ccc23)N2CCOCC2)CC1 Show InChI InChI=1S/C27H29N7O2/c1-32-7-9-33(10-8-32)17-18-15-21-23-24(36-27(21)29-16-18)26(34-11-13-35-14-12-34)31-25(30-23)20-3-2-4-22-19(20)5-6-28-22/h2-6,15-16,28H,7-14,17H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Lek Pharmaceuticals d.d.					Assay Description Please see article				J Med Chem 51: 7486-94 (2008) BindingDB Entry DOI: 10.7270/Q21V5H9P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM291362 (2-(1H-Indol-4-yl)-8-(4-methyl-piperazin-1-ylmethyl...) Show SMILES CN1CCN(Cc2cnc3oc4c(nc(nc4c3c2)-c2cccc3[nH]ccc23)N2CCOCC2)CC1 Show InChI InChI=1S/C27H29N7O2/c1-32-7-9-33(10-8-32)17-18-15-21-23-24(36-27(21)29-16-18)26(34-11-13-35-14-12-34)31-25(30-23)20-3-2-4-22-19(20)5-6-28-22/h2-6,15-16,28H,7-14,17H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Karus Therapeutics Limited US Patent					Assay Description PI3K Isoform using biochemical assay.				US Patent US9580442 (2017) BindingDB Entry DOI: 10.7270/Q2J38VM2
					More data for this Ligand-Target Pair