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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Potassium channel subfamily K member 3' and Ligand = 'BDBM218483'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium channel subfamily K member 3


(Homo sapiens (Human))
BDBM218483
PNG
(US9284333, 16is | US9884860, Example 16is)
Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)NCc2ccc(CC(=O)OC)cc2)n2CCOCc12)c1ccccc1 |r|
Show InChI InChI=1S/C28H31N3O5/c1-3-23(21-7-5-4-6-8-21)30-27(33)22-16-24(31-13-14-36-18-25(22)31)28(34)29-17-20-11-9-19(10-12-20)15-26(32)35-2/h4-12,16,23H,3,13-15,17-18H2,1-2H3,(H,29,34)(H,30,33)/t23-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.70E+3n/an/an/an/an/a25



Sanofi

US Patent


Assay Description
Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...


US Patent US9884860 (2018)


BindingDB Entry DOI: 10.7270/Q2862JGT
More data for this
Ligand-Target Pair
Potassium channel subfamily K member 3


(Homo sapiens (Human))
BDBM218483
PNG
(US9284333, 16is | US9884860, Example 16is)
Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)NCc2ccc(CC(=O)OC)cc2)n2CCOCc12)c1ccccc1 |r|
Show InChI InChI=1S/C28H31N3O5/c1-3-23(21-7-5-4-6-8-21)30-27(33)22-16-24(31-13-14-36-18-25(22)31)28(34)29-17-20-11-9-19(10-12-20)15-26(32)35-2/h4-12,16,23H,3,13-15,17-18H2,1-2H3,(H,29,34)(H,30,33)/t23-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.70E+3n/an/an/an/an/a25



Sanofi

US Patent


Assay Description
Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...


US Patent US9284333 (2016)


BindingDB Entry DOI: 10.7270/Q2FJ2FMC
More data for this
Ligand-Target Pair