Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM50086497'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50086497 (3-(4-Chloro-phenyl)-5-fluoro-1-(4-methoxy-phenyl)-...) Show SMILES COc1ccc(cc1)-n1nc(c2CC(F)CCc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H18ClFN2O/c1-25-17-9-7-16(8-10-17)24-19-11-6-15(22)12-18(19)20(23-24)13-2-4-14(21)5-3-13/h2-5,7-10,15H,6,11-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against human prostaglandin G/H synthase 1 in platelet-rich plasma measured by the presence of thromboxane A2				Bioorg Med Chem Lett 10: 601-4 (2000) BindingDB Entry DOI: 10.7270/Q2TH8KWZ
					More data for this Ligand-Target Pair