BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protease' and Ligand = 'BDBM50480937'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protease


(Human immunodeficiency virus 1 (HIV-1))		BDBM50480937
PNG
(CHEMBL583564)
Show SMILES COC(=O)N[C@H](C(=O)NN(CC[C@@](O)(Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12)Cc1ccc(cc1)-c1c(C)noc1C)C(C)(C)C |r|
Show InChI InChI=1S/C40H49N5O7/c1-25-33(26(2)52-44-25)29-18-16-28(17-19-29)24-45(43-36(47)35(39(3,4)5)42-38(49)51-6)21-20-40(50,23-27-12-8-7-9-13-27)37(48)41-34-31-15-11-10-14-30(31)22-32(34)46/h7-19,32,34-35,46,50H,20-24H2,1-6H3,(H,41,48)(H,42,49)(H,43,47)/t32-,34+,35-,40-/m1/s1
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 2.80n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 protease expressed in Escherichia coli by fluorometric assay

J Med Chem 53: 607-15 (2010)


Article DOI: 10.1021/jm901165g
BindingDB Entry DOI: 10.7270/Q29Z97R7
More data for this
Ligand-Target Pair