Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM337059'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM337059 (US9745291, Compound 105 | US9765068, Compound 105) Show SMILES CN(C)c1ccc2cccc(OCC(=O)NC[C@@H](O)CN3CCc4ccccc4C3)c2n1 |r| Show InChI InChI=1S/C25H30N4O3/c1-28(2)23-11-10-19-8-5-9-22(25(19)27-23)32-17-24(31)26-14-21(30)16-29-13-12-18-6-3-4-7-20(18)15-29/h3-11,21,30H,12-17H2,1-2H3,(H,26,31)/t21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description Molecular Biology: Full-length human PRMT5 (NM_006109.3) transcript variant 1 clone was amplified from a fetal brain cDNA library, incorporating flan...				US Patent US9765068 (2017) BindingDB Entry DOI: 10.7270/Q2959KN3
					More data for this Ligand-Target Pair