Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50100300'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50100300 (2-(2,4-Dichloro-phenylsulfanyl)-4-imidazol-1-ylmet...) Show SMILES Clc1ccc(Sc2cc(Cn3ccnc3)ccc2C#N)c(Cl)c1 Show InChI InChI=1S/C17H11Cl2N3S/c18-14-3-4-16(15(19)8-14)23-17-7-12(1-2-13(17)9-20)10-22-6-5-21-11-22/h1-8,11H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rate of incorporation of [3H]-GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-tran...				Bioorg Med Chem Lett 11: 1257-60 (2001) BindingDB Entry DOI: 10.7270/Q2FX78RS
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50100300 (2-(2,4-Dichloro-phenylsulfanyl)-4-imidazol-1-ylmet...) Show SMILES Clc1ccc(Sc2cc(Cn3ccnc3)ccc2C#N)c(Cl)c1 Show InChI InChI=1S/C17H11Cl2N3S/c18-14-3-4-16(15(19)8-14)23-17-7-12(1-2-13(17)9-20)10-22-6-5-21-11-22/h1-8,11H,10H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rate of incorporation of [3H]-GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-tran...				Bioorg Med Chem Lett 11: 1257-60 (2001) BindingDB Entry DOI: 10.7270/Q2FX78RS
					More data for this Ligand-Target Pair