Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein-S-isoprenylcysteine O-methyltransferase' and Ligand = 'BDBM50327725'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human))	BDBM50327725 (3-(1-octyl-5-m-tolyl-1H-indol-3-yl)propanamide | C...) Show SMILES CCCCCCCCn1cc(CCC(N)=O)c2cc(ccc12)-c1cccc(C)c1 Show InChI InChI=1S/C26H34N2O/c1-3-4-5-6-7-8-16-28-19-23(13-15-26(27)29)24-18-22(12-14-25(24)28)21-11-9-10-20(2)17-21/h9-12,14,17-19H,3-8,13,15-16H2,1-2H3,(H2,27,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation counting				J Med Chem 53: 6838-50 (2010) Article DOI: 10.1021/jm1002843 BindingDB Entry DOI: 10.7270/Q2VT1SB1
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