Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein-S-isoprenylcysteine O-methyltransferase' and Ligand = 'BDBM50327727'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human))	BDBM50327727 (CHEMBL1257398 | ethyl 2-(1-octyl-5-m-tolyl-1H-indo...) Show SMILES CCCCCCCCn1cc(CC(=O)OCC)c2cc(ccc12)-c1cccc(C)c1 Show InChI InChI=1S/C27H35NO2/c1-4-6-7-8-9-10-16-28-20-24(19-27(29)30-5-2)25-18-23(14-15-26(25)28)22-13-11-12-21(3)17-22/h11-15,17-18,20H,4-10,16,19H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation counting				J Med Chem 53: 6838-50 (2010) Article DOI: 10.1021/jm1002843 BindingDB Entry DOI: 10.7270/Q2VT1SB1
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