Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein-S-isoprenylcysteine O-methyltransferase' and Ligand = 'BDBM50327739'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human))	BDBM50327739 (CHEMBL1257982 | N-ethyl-N-((5-fluoro-1-(3-methylbu...) Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6]-c1cn(-[#6]\[#6]=[#6](\[#6])-[#6])c2ccc(F)cc12 Show InChI InChI=1S/C18H25FN2/c1-5-20(6-2)12-15-13-21(10-9-14(3)4)18-8-7-16(19)11-17(15)18/h7-9,11,13H,5-6,10,12H2,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation counting				J Med Chem 53: 6838-50 (2010) Article DOI: 10.1021/jm1002843 BindingDB Entry DOI: 10.7270/Q2VT1SB1
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