Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus) | BDBM374916![]() (N-(2,3'-bipyridin-6'-yl)-2-(2',3-dimethyl-2,4'-bip...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine... | ACS Med Chem Lett 7: 676-80 (2016) Article DOI: 10.1021/acsmedchemlett.6b00038 BindingDB Entry DOI: 10.7270/Q2FB56F9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus) | BDBM374916![]() (N-(2,3'-bipyridin-6'-yl)-2-(2',3-dimethyl-2,4'-bip...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine... | ACS Med Chem Lett 7: 676-80 (2016) Article DOI: 10.1021/acsmedchemlett.6b00038 BindingDB Entry DOI: 10.7270/Q2FB56F9 | |||||||||||
More data for this Ligand-Target Pair |