Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-1' and Ligand = 'BDBM182669'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM182669 (US9145392, 370) Show SMILES CC(C)NCCn1cc(nc1C1CCN(CC1)c1ncnc(N)c1C(N)=O)-c1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C25H30F4N8O/c1-14(2)32-7-10-37-12-19(16-3-4-18(26)17(11-16)25(27,28)29)35-23(37)15-5-8-36(9-6-15)24-20(22(31)38)21(30)33-13-34-24/h3-4,11-15,32H,5-10H2,1-2H3,(H2,31,38)(H2,30,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.5	25
Merck Patent GmbH US Patent					Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...				US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2
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