Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase 24' and Ligand = 'BDBM451741'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 24 (Homo sapiens (Human))	BDBM451741 (N-(4-(6-amino-5-(1-oxo- 1,2,3,4-tetrahydroisoquino...) Show SMILES Nc1ncc(cc1-c1ccc2C(=O)NCCc2c1)-c1ccc(NS(=O)(=O)C2CC2)cc1F Show InChI InChI=1S/C23H21FN4O3S/c24-21-11-16(28-32(30,31)17-3-4-17)2-6-18(21)15-10-20(22(25)27-12-15)13-1-5-19-14(9-13)7-8-26-23(19)29/h1-2,5-6,9-12,17,28H,3-4,7-8H2,(H2,25,27)(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020) BindingDB Entry DOI: 10.7270/Q2J67KZW
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